Anti-TGFβ1 抗體





應用於人類、mouserat物種;應用IHC測試,確定可用於IHC實驗。建議使用量1:50~1:200倍稀釋。









TGF beta1 Antibody











































































Antibody
Type



primary
antibody



Accession
#



NM_000660



Description



TGF
beta1 is a TGFB is a multifunctional peptide that controls proliferation,
differentiation, and other functions in many cell types. TGFB acts
synergistically with TGFA (MIM 190170) in inducing transformation. It also
acts as a negative autocrine growth factor. Dysregulation of TGFB activation
and signaling may result in apoptosis. Many cells synthesize TGFB and almost
all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM
190220), and TGFB3 (MIM 190230) all function through the same receptor
signaling systems.[



Immunogen



partial
recombinate protein



Species
Reactivity



human,mus,rattus



Specificity



TGF
beta1 antibody detects endogenous levels of TGF1 beta1 protein. Not tested
with other proteins



Tested
Applications



Peptide
ELISAWB:1:500 IHC



Application
Notes



Recommended
dilutions Peptide ELISA: 1:80,000 WB: 1/200 - 1/1000 IHc:1/50-1/200 Not yet
tested in other applications. Optimal dilutions/concentrations should be
determined by the end user



Raised
In



Rabbit



Clonality



Polyclonal



Purity



Protein
A purified



Storage
Buffer



Rabbit
IgG containing 0.02% sodium azide



Formulation



Liquid



Concentration



100ug/100ul



Storage



Store
at -20°C /1 year



References



Korff,T.,
Aufgebauer,K. and Hecker,M Cyclic stretch controls the expression of CD 40 in endothelial cells by changing their
transforming growth factor-beta1 response

Circulation 2007:116 (20), 2288-2297



Caution



TGF
beta1 is for research use only and is not intended for therapeutic or
diagnostic applications. Please contact a technical service representative
for more information.





 





 


 


 

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