太鼎生物科技/太鼎食安科技

Antibody
Type

primary
antibody

Accession
#

NM_000660

Description

TGF
beta1 is a TGFB is a multifunctional peptide that controls proliferation,
differentiation, and other functions in many cell types. TGFB acts
synergistically with TGFA (MIM 190170) in inducing transformation. It also
acts as a negative autocrine growth factor. Dysregulation of TGFB activation
and signaling may result in apoptosis. Many cells synthesize TGFB and almost
all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM
190220), and TGFB3 (MIM 190230) all function through the same receptor
signaling systems.[

Immunogen

partial
recombinate protein

Species
Reactivity

human,mus,rattus

Specificity

TGF
beta1 antibody detects endogenous levels of TGF1 beta1 protein. Not tested
with other proteins

Tested
Applications

Peptide
ELISAWB:1:500 IHC

Application
Notes

Recommended
dilutions Peptide ELISA: 1:80,000 WB: 1/200 - 1/1000 IHc:1/50-1/200 Not yet
tested in other applications. Optimal dilutions/concentrations should be
determined by the end user

Raised
In

Rabbit

Clonality

Polyclonal

Purity

Protein
A purified

Storage
Buffer

Rabbit
IgG containing 0.02% sodium azide

Formulation

Liquid

Concentration

100ug/100ul

Storage

Store
at -20°C /1 year

References

Korff,T.,
Aufgebauer,K. and Hecker,M Cyclic stretch controls the expression of CD 40 in endothelial cells by changing their
transforming growth factor-beta1 response

Circulation 2007:116 (20), 2288-2297

Caution

TGF
beta1 is for research use only and is not intended for therapeutic or
diagnostic applications. Please contact a technical service representative
for more information.