Imm-Link】產品,可於Peptides 或有機化合物(organic compounds)等小分子進行標誌,其標誌的種類如BSAOvalbuminKeyhole Limpet Hemocyanin (KLH)。可應用於產製carrier proteins,誘發免疫系統產生大量的抗體。依不同的需要,可標誌於蛋白質上不同的位置 Sulfhydryl Carboxylamino



 


immLink


 


Imm-link產品特點】



  • All components supplied.
  • Wide range of chemistries.
  • Hands on time to set up conjugation reaction is 20-30 seconds.
  • Supplied dialysis cartridge ensures conjugates are recovered in high yield.

BSA, Ovalbumin or Keyhole Limpet Hemocyanin (KLH) stimulate a large immune response and are typically used as carrier proteins to generate antibodies against small antigens (peptides or organic compounds). For success the antigen (normally referred to as a hapten) needs to be covalently linked to the carrier protein.


The imm-Link™ sulfhydryl conjugation kit allows sulfhydryl containing haptens to be conjugated to a carrier protein simply by adding a solution of the hapten to a proprietary lyophilised mixture containing the carrier protein and all the required conjugation chemistry. The hands-on time to set up the conjugation reaction is typically 20-30 seconds.


Following successful conjugation the conjugate is dialysed in the supplied dialysis cartridge to remove unwanted by products. The hapten conjugate can then be easily recovered and used.











Immunogen Kit



Sulfhydryl



Target Functional Groups



Cysteines or free sulfhydryl groups (SH)



Immunogen Kits







imm-Link™ Sulfhydryl Immunogen Kits


 






imm-Link™ Carboxyl Immunogen Kits


 






imm-Link™ Amine Immunogen Kits


Innova Biosciences Launches New Immunogen Conjugation Kits


INNOVA BIOSCIENCES集力開發免疫標誌產品
Innova Biosciences (Cambridge, UK) the inventor of the World's easiest to use antibody labeling kits, has extended its product portfolio.

    CAMBRIDGE, ENGLAND, February 24, 2011 /Science and Research PR News/ -- Innova Biosciences (Cambridge, UK) the inventor of the World's easiest to use antibody labeling kits, has extended its product portfolio. For scientists to generate novel antibodies, it is necessary to perform a conjugation reaction (the joining of two molecules) to link the target protein or peptide to a carrier protein such as BSA or Ovalbumin. Conjugation reactions are traditionally daunting and laborious to the non-specialist.

Innova Biosciences imm-Link kits have been designed to take the difficulty out of this conjugation process through simplifying both the linking chemistry and the methodology itself - the conjugate is created simply by adding the target protein or peptide to a freeze dried mixture containing the relevant chemistry and the carrier protein.


 


更多參考內容:


 


原廠連結: http://www.innovabiosciences.com/


 


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