【SouthernBiotech代理品牌】一抗/二抗 @ 太鼎生物科技/太鼎食安科技

膠原蛋白Type I Rat Collagen |ECM Protein 貨號1200-03

SouthernBiotech高品質膠原Collagen

品牌商品繪圖 250x250 SBA _工作區域 1_工作區域 1_工作區域 1.jpg

關於膠原（Collagen）：

膠原蛋白是動物結締組織重要的蛋白質,在哺乳動物中的含量尤為豐富，佔有機體蛋白質百分之25%-35%含量。膠原是細胞外最重要的水不溶性纖維蛋白, 是構成細胞外基質（extracellular matrix, ECM）的骨架。膠原在細胞外基質中形成半晶體的纖維,給細胞提供抗張力和彈性,並在細胞的遷移和發育中起作用。膠原蛋白的基本結構單位是原膠原(tropocollagen), 原膠原肽鏈的一級結構具有(Gly-x-y)n重複序列, 其中x常為脯氨酸(Pro), y常為羥脯氨酸(Hypro)或羥賴氨酸(Hylys)。Hylys殘基可發生糖基化修飾,其糖單位有的是一個半乳糖殘基(Gal), 但通常是二糖(Glu-Gal-),膠原上的糖所占的量約為膠原的10%。原膠原是由三條α-肽鏈組成的纖維狀蛋白質, 相互擰成三股螺旋狀構型, 長300nm, 直徑1.5nm。目前已發現29種不同組織中不同類型的膠原; 不同類型的膠原定位於體內的特定組織,也有2-3種不同的膠原存在於同一組織中。而機體內90%的膠原為I、II、III、IV型。

膠原蛋白

產品名稱	編號（cat#）	包裝形式	規格
Type I Human Collagen	1200-01S	溶液	0.50mg
Type I Bovine Collagen	1200-02/1200-02S	凍乾粉/溶液	0.25mg/0.50mg
Type I Rat Collagen	1200-03/1200-03S	凍乾粉/溶液	0.25mg/0.50mg
Type II Rat Collagen	1220-02/1220-02S	凍乾粉/溶液	0.25mg/0.50mg
Type III Human Collagen	1230-01S	溶液	0.50mg
Type III Bovine Collagen	1240-02S	溶液	0.50mg
Type IV Human Collagen	1250-01S	溶液	0.50mg
Type IV Mouse Collagen	1250-04S	溶液	0.50mg
Type IV Bovine Collagen	1260-02	凍乾粉	0.25mg
Type V Human Collagen	1270-01/1270-01S	凍乾粉/溶液	0.1mg/0.25mg
Type V Bovine Collagen	1280-02S	溶液	0.25mg
Type VI Human Collagen	1290-01S	溶液	0.25mg
Type VI Bovine Collagen	1300-02/1300-02S	凍乾粉/溶液	0.10mg/0.25mg

膠原蛋白多株抗體

產品名稱	編號（cat#）	包裝形式	規格
Goat Anti-Type I Collagen	1310-01/1310-08	未標記/生物素化	0.2mg/0.2mg
Goat Anti-Type II Collagen	1320-01/1320-08	未標記/生物素化	0.2mg/0.2mg
Goat Anti-Type III Collagen	1330-01/1330-08	未標記/生物素化	0.2mg/0.2mg
Goat Anti-Type IV Collagen	1340-01/1340-08	未標記/生物素化	0.2mg/0.2mg
Goat Anti-Type V Collagen	1350-01/1350-08	未標記/生物素化	0.2mg/0.2mg
Goat Anti-Type VI Collagen	1360-01/1360-08	未標記/生物素化	0.2mg/0.2mg

膠原蛋白單株抗體

產品名稱	編號（cat#）	包裝形式	規格
Mouse Anti-Human Type I Collagen	1440(1)-01	未標記	0.1mg
Mouse Anti-Human Type IV Collagen	1460-01	未標記	0.1mg
Mouse Anti-Human Type IV Collagen	1460-02	FITC	0.1mg
Mouse Anti-Human Type IV Collagen	1460-08	BIOT	0.1mg
Mouse Anti-Human Type IV Collagen	1460-09	R-PE	0.1mg

應用： ELISA、免疫螢光、免疫細胞化學、免疫組織化學（冰凍切片）

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Mouse Anti-Human IgG Fc-UNLB (JDC-10)抗體 | 貨號9040-01規格0.5mg (0.5 mg/ml, 1ml)

產品介紹: 純化的抗人 IgG Fc 抗體(Purified Anti-Human IgG Fc antibody)，應用於 ELISA、流式細胞術(flow cytometry)、免疫組織化學(immunohistochemistry)、蛋白質印跡(western blot)和多重檢測(multiplex assays)。

SBA 代理商品.png

Clone	JDC-10
Isotype	Mouse IgG₁κ
Isotype Control	Mouse IgG1-UNLB (15H6)
Specificity	Human/Rhesus/Chimpanzee IgG Fc
Immunogen	Purified human IgG₁ myeloma protein
Conjugate	UNLB (Unconjugated)
Buffer Formulation	Borate buffered saline, pH 8.2
Clonality	Monoclonal
Concentration	0.5 mg/mL
Volume	1.0 mL
Recommended Storage	2-8°C
Applications	ELISA – Quality tested ^1-15,20 FLISA – Quality tested Flow Cytometry – Quality tested ^18,19 Immunohistochemistry-Paraffin Sections – Reported in literature ¹⁶ Western Blot – Reported in literature ¹⁷ Multiplex – Reported in literature ^20-22
RRID Number	AB_2796598

細胞免疫專家極力推薦SouthernBiotech高品質二級抗體

美國抗體生產商Southern Biotech於1982年，由UAB細胞免疫專家Dr. Max Cooper與實驗室成員共同創立。SouthernBiotech致力於生產高品質二級抗體。物種種類齊全，包括有Bovine、Canine、Chicken、Cynomolgus、Donkey、Equine、Feline、Goat、Guinea Pig、Hamster、Human、Monkey、Mouse、Porcine、Rabbit、Rat、Rhesus、Sheep、Turkey。具有螢光物質（FITC、PE、APC、SPRD、PE/CY5.5、APC/CY5.5、Spectral Red、Alexa 488、Alexa 647、Pacific Blue）各種螢光標誌、另具酵素（HRP、AP）、或未標誌及Low Endotoxin/Azide Free（LE/AF）等標定。

品牌商品繪圖 250x250 SBA _工作區域 1_工作區域 1_工作區域 1.jpg

SouthernBiotech 抗小鼠二抗(anti-mouse secondary antibodies)是經過廣泛表徵的親和純化(affinity-purified)的多克隆(polyclonal)或單克隆抗體(monoclonal antibodies)，對小鼠免疫球蛋白重鏈類別(mouse immunoglobulin heavy chain classes)和亞類(subclasses)、輕鍊(light chains)和片段(fragments)具有特異性(specificities)。SouthernBiotech提供在山羊(goat)、兔(rabbit)、驢(donkey)和大鼠(rat)中產生的抗小鼠二抗。它們在檢測一抗(primary antibodies )方面很有價值，並且有多種形式可供選擇，包括未偶聯以及酶、生物素化和螢光偶聯物，用於 ELISA、蛋白質印跡(western blot)、流式細胞術(flow cytometry)、多重和免疫組織化學(immunohistochemistry)等分析。

由於單克隆抗體 ( monoclonal antibodies )將結合抗體靶標上的單個表位，因此它們具有高度特異性(specific)，可提供出色的批次間一致性(lot-to-lot consistency)，並且通常在文獻中得到很好的表徵。我們的多克隆抗小鼠二抗(polyclonal anti-mouse secondary antibodies)可以通過信號放大提高靈敏度(sensitivity)，因為多個二抗可以與單個一抗結合。

選定的抗體已與來自其他物種的 IgG 和/或血清蛋白交叉吸附，以產生對這些物種具有最小交叉反應性(cross-reactivity)的抗體。使用對您的樣品物種具有最小交叉反應性的二抗非常重要。通過提供全面的多克隆(polyclonal)和單克隆(monoclonal)抗小鼠類(anti-mouse class)和亞類特異性二抗（例如 IgG1、IgG2b、IgM），可以在測定中同時檢測多種小鼠一抗。我們有廣泛的全分子和F(ab’)₂ fragment 片段多克隆和單克隆抗小鼠抗體可供選擇，所有這些抗體都是內部生產和驗證的，可用於您的特定檢測。

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2. Chapuy-Regaud S, Nogueira L, Clavel C, Sebbag M, Vincent C, Serre G. IgG subclass distribution of the rheumatoid arthritis-specific autoantibodies to citrullinated fibrin. Clin Exp Immunol. 2005;139:542-50. (ELISA)
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4. Adekar SP, Jones RM, Elias MD, Al-Saleem FH, Root MJ, Simpson LL, et al. Hybridoma populations enriched for affinity-matured human IgGs yield high-affinity antibodies specific for botulinum neurotoxins. J Immunol Methods. 2008;333:156-66. (ELISA)
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11. Beaumont E, Patient R, Hourioux C, Dimier-Poisson I, Roingeard P. Chimeric hepatitis B virus/hepatitis C virus envelope proteins elicit broadly neutralizing antibodies and constitute a potential bivalent prophylactic vaccine. Hepatology. 2013;57:1303-13. (ELISA)
12. Dimitrov JD, Planchais C, Scheel T, Ohayon D, Mesnage S, Berek C, et al. A cryptic polyreactive antibody recognizes distinct clades of HIV-1 glycoprotein 120 by an identical binding mechanism. J Biol Chem. 2014;289:17767-79. (ELISA)
13. Einarsdottir HK, Stapleton NM, Scherjon S, Andersen JT, Rispens T, van der Schoot CE, et al. On the perplexingly low rate of transport of IgG2 across the human placenta. PLoS One. 2014;9(9):e108319. (ELISA)
14. Westra J, van Assen S, Wilting KR, Land J, Horst G, de Haan A, et al. Rituximab impairs immunoglobulin (Ig)M and IgG (subclass) responses after influenza vaccination in rheumatoid arthritis patients. Clin Exp Immunol. 2014;178:40-7. (ELISA)
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18. Leyendeckers H, Odendahl M, Löhndorf A, Irsch J, Spangfort M, Miltenyi S, et al. Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG. Eur J Immunol. 1999;29:1406-17. (FC)
19. Cortez VS, Cervantes-Barragan L, Song C, Gilfillan S, McDonald KG, Tussiwand R, et al. CRTAM controls residency of gut CD4⁺CD8⁺ T cells in the steady state and maintenance of gut CD4⁺ Th17 during parasitic infection. J Exp Med. 2014;211:623-33. (FC)
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23. Nonhuman Primate Reagent Resource (Rhesus & Chimpanzee Reactivity)