8-Br-cAMP誘導細胞分化

Catalog#:
1837-25 | Size: 25 mg





8--環腺苷酸(8-bromo-cyclic 3
5 -adenosine monophosphat8-Br-cAMP)可選擇性結合cAMP受體位點,誘導細胞分化





Description: A cell-permeable cAMP analog that is more resistant to
hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A,
inhibits growth, decreases proliferation, increases differentiation, and
induces apoptosis of cultured cells. Also recently shown to improve the
reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells
2-fold.





Alternate Name/Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8-
bromoadenosine- 3', 5'- monophosphate





Appearance: White to off-white solid





CAS Number: 76939-46-3





Molecular Formula: C₁₀H₁₀BrNOP. Na





Molecular Weight: 430.08





Purity: 98%
by TLC





Solubility: HO
(~100 mg/ml)





Storage Temp.: -20°C





Shipping Conditions: gel pack





Handling: Protect from moisture and light





USAGE: For Research Use Only! Not For
Use in Humans





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