奈米金GOLD Biotin 貨號#240-0200 (200ul); 貨號#240-1000 (1000ul)
A Revolution in GOLD Biotin
InnovaCoat專利研發GOLD Biotin,可直接應用於lateral flow test快篩試驗的開發, 可結合biotin標誌之抗體，大幅提高快篩之靈敏度。InnovaCoat™GOLD表面具有獨特塗層保護, 此納米粒子可承受最極端的條件下（如2.5M的NaOH在70℃〜2小時）。以共價鍵結將streptavidin附著於奈米金，性質穩定。廣泛應用於lateral flow test、電鏡、免疫、分子生物學以至生物晶片中。
1. 表面獨特coating. 將Biotin以共價鍵結於奈米金上。性質穩定
3. 光學密度10 O.D. (40nm)
InnovaCoat™ GOLD is a unique coated nanoparticle that has an avidly bound protective surface coat which can withstand the most extreme conditions (e.g. 2.5M NaOH at 70oC for ~2 hours).
By covalently attaching streptavidin to the surface coat the resulting InnovaCoat™ GOLD-Streptavidin nanoparticles inherit the stability attributes of the core nanoparticle; moreover the streptavidin ligand cannot desorb, which is a major problem with all the competing products in which the streptavidin is directly attached to the metal.
InnovaCoat™ GOLD - 20OD 40nm Gold Particle Kits, 230-0010
InnovaCoat™ GOLD products are‘conjugation friendly’ nanoparticles with a proprietary surface coat that greatly enhances colloidal stability and permits easy covalent attachment of a variety of molecules, including antibodies, analytes and other biomolecules.
In the case of immuno-gold conjugates, the antibody can be attached irreversibly without the need for extensive trials at different values of pH and/or salt concentration, as is typical of traditional ‘passive’ binding methods.
In the case of analyte-gold conjugates, the multipoint attachment of the polymer to the gold surface ensures that the analyte is firmly anchored. By contrast, direct attachment of analytes to gold surfaces by self-assembly techniques is far less stable and unwanted desorption is a significant problem.
InnovaCoat™ GOLD nanoparticles can be provided in a variety of formats (e.g. 10 OD liquid or as lyophilized nanoparticles) formulated to allow a one-step reaction with antibodies.
The kits available are designed for research use and for the development of diagnostic products, specifically for the screening of potential antibodies or small scale ‘proof of principle’studies. Please contact us if you require any additional information and to discuss your bulk or custom conjugation requirements.