【H5N1-2011-HA蛋白質】H5N1甲型流感病毒蛋白質, 貨號#40015-V08H。sino biological－太鼎生物科技/太鼎食安科技

H5N1 ( A/Hubei/2011 ) HA Protein Price Inquiry ( Available Sizes )H5N1甲型流感病毒蛋白質

200μg: Inquiring Price;
≥1mg Bulk: Inquiring Price

H5N1 ( A/Hubei/2011 ) HA Protein Product Information

Synonym :	HA
Protein Construction:	A DNA sequence encoding the extracellular domain of influenza A virus hemagglutinin ( A/Hubei/2011 ( H5N1 ) ) ( Met 1 - Gln 530 ) ( HA1 + HA2, cleaved) was fused with a polyhistidine tag at the C-terminus.
Source:	Influenza A Virus H5N1
Expression Host:	Human Cells

H5N1 ( A/Hubei/2011 ) HA Protein QC Testing

Purity:	> 90 % as determined by SDS-PAGE	SDS-PAGE: H5N1 HA protein
Endotoxin:	< 1.0 EU per μg of the protein as determined by the LAL method
Stability:	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal:	Asp 17
Molecular Mass:	The secreted recombinant hemagglutinin of influenza A virus H5N1 ( A/Hubei/2011 ) comprises 525 amino acids and has a predicted molecular mass of 60.1 kDa. As a result of glycosylation, it migrates as an approximately 65-70 kDa band in non-reduced SDS-PAGE, and three bands ( 25, 45, 70 kDa ) in reduced SDS-PAGE
Formulation:	Lyophilized from sterile PBS , pH 7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

H5N1 ( A/Hubei/2011 ) HA Protein Usage Guide

Storage:	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

H5N1 ( A/Hubei/2011 ) HA Protein Related Products & Topics

Related Areas:

Proteins:

Antibodies:

H5N1 ( A/Hubei/2011 ) HA Protein Description

Hemagglutinin (HA) is a single-pass type I integral membrane glycoprotein from the influenza virus, and comprises over 80% of the envelope proteins present in the virus particle. The HA is a trimer with a receptor binding pocket on the globular head of each monomer. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoprotease secreted by the bronchial epithelial cells. Binding of HA to sialic acid-containing receptors on the surface of its target cell brings about the attachment of the virus particle to the cell and forms a endosome. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the hydrophobic portion “fusion peptide”. After which, virus penetrates the cell and pours its contents including the RNA genome into the cytoplasm mediated by fusion of the endocytosed virus particle’s own membrane and the endosomal membrane. Hemagglutinin plays a major role in the determination of host range restriction and virulence.