Cell Damage & Oxidative Stress
While histone acetylation provides increased accessibility of transcription factors to DNA, the deacetylation of histones is associated with transcriptional silencing. Oxidative stress is often defined as an imbalance of pro-oxidants and antioxidants. Oxidative stress and the associated damage to cellular lipids, proteins and DNA can contribute to a decline in cellular function, leading to a number of human pathologies. BioVision offers various convenient kits for analyzing transcriptional regulation, DNA damage, oxidative stress, energy transforming and redox state, and more are coming in the pipeline.
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