【H7N9 NP單株抗體】#11675-R707。Anti-H7N9 NP / Nucleoprotein Antibody－太鼎生物科技/太鼎食安科技

Anti-H7N9 NP / Nucleoprotein
Antibody

H7N9 NP單株抗體

原廠操件手冊

Anti-H7N9 NP /
Nucleoprotein Antibody Product Information

Antibody Type :	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID :	705
Ig Type :	Rabbit IgG
Formulation :	0.2 μm filtered solution in PBS with 5% trehalose

Anti-H7N9 NP /
Nucleoprotein Antibody Usage Guide

Specificity :	Anti-H7N9 NP / Nucleoprotein
	*Has cross-reactivity* in ELISA with H7N9 (A/Anhui/1/2013) NP H7N9 (A/Shanghai/1/2013) NP
Applications :	ELISA (Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.)
Direct ELISA :	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect H7N9 (A/Anhui/1/2013) NP and H7N9 (A/Shanghai/1/2013) NP. The detection limit for both H7N9 (A/Anhui/1/2013) NP and H7N9 (A/Shanghai/1/2013) NP are approximately 0.0049 ng/well.
Storage :	This antibody can be stored at 2℃ -8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃ . Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-H7N9
NP / Nucleoprotein Antibody Related Products & Topics

Related Areas:

Proteins:

Antibodies:

Anti-H7N9 NP / Nucleoprotein Antibody
Background

H7N9 is a subtype of Influenza
virus A. On April 1, 2013, the World Health Organization (WHO) first reported 3
human infections with a new influenza A (H7N9) virus in China . Since
then, additional cases have been reported. This new H7N9 virus is an avian
(bird) influenza (flu) virus. Influenza (flu) is a respiratory infection in
mammals and birds. The virus is divided into three main types (Influenza A,
Influenza B, and Influenza C). The influenza A genome contains 11 genes on
eight pieces of RNA, encoding for 11 proteins: Hemagglutinin (HA),
Neuraminidase (NA), Nucleoprotein (NP), M1, M2, NS1, NS2 (NEP), PA, PB1, PB1-F2
and PB2.

Influenza A virus nucleoprotein
(NP) forms homo-oligomers and multiple copies of NP wrap around genomic RNA,
along with a trimeric polymerase making up ribonucleoprotein (RNP) complex.
Nucleoprotein (NP) is composed of a head and a body domain and a tail loop /
linker region. The head domain is more conserved than the body domain. Nucleoprotein
(NP) oligomerization is mediated by the insertion of the non-polymorphic and
structurally conserved tail loop of one NP molecule to a groove of another NP.
The different form of Nucleoprotein (NP) oligomers is due to the flexibility of
the polymorphic linkers that join the tail loop to the rest of the protein. The
RNA binding property of NP is known to involve the protruding element and the
flexible basic loop between the head and body domains, both having high degree
of primary sequence conservation.