【H6N1單株抗體】#11723-MM04, 100UG。可應用於WB及ELISA試驗。Influenza A H6N1 HA / Hemagglutinin Antibody－太鼎生物科技/太鼎食安科技

H6N1
流感抗體

Influenza A H6N 1
HA / Hemagglutinin Antibody

產品型號及datasheet下載: 11723-MM04

可應用於WB及ELISA之分析

偵測靈敏度: WB (2 ng/lane)

ELISA( 0.039 ng/well
)

H6N1 Hemagglutinin
/ HA Antibody Product Information

Immunogen :	Recombinant H6N 1 HA protein
Antibody Type :	Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
Clone ID :	8A10D8
Ig Type :	Mouse IgG1
Formulation :	0.2 μm filtered solution in PBS with 5% trehalose
Preparation :	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant Influenza A virus H6N1 Hemagglutinin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

H6N1
Hemagglutinin / HA Antibody Usage Guide

Specificity :	H6N1 (A/northern shoveler/California/HKWF115/2007) HA
	No cross-reactivity in ELISA with H1N1 (A/California/07/2009) HA H2N2 (A/Canada/720/2005) HA H3N2 (A/Wyoming/03/2003) HA H4N6 (A/mallard/Ohio/657/2002) HA H5N1 (A/Anhui/1/2005) HA H7N7 (A/chicken/Netherlands/1/03) HA H8N4 (A/pintail duck/Alberta/114/1979) HA H9N2 (A/Hong Kong/1073/99) HA H10N3 (A/duck/Hong Kong/786/1979) HA H11N2 (A/duck/Yangzhou/906/2002) HA H12N5 (A/green-winged teal/ALB/199/1991) HA H13N8 (A/black-headed gull/Netherlands/1/00) HA H15N8 (A/duck/AUS/341/1983) HA H16N3 (A/black-headed gull/Sweden/5/99) HA Influenza B (B/Florida/4/2006) HA
Western blot :	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect H6N1-HA in WB. Using a DAB detection system, the detection limit for H6N1-HA is approximately 4 ng/lane under non-reducing conditions and 2 ng/lane under reducing conditions.
Direct ELISA :	This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect H6N1-HA. The detection limit for H6N1-HA is approximately 0.039 ng/well.
Storage :	This antibody can be stored at 2℃ -8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃ . Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

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A/northern
shoveler/California/HKWF115/2007

H6N1 Hemagglutinin / HA Antibody Description

Influenza (flu) is a respiratory infection in mammals and
birds. This virus is divided into three main types (A, B and C). Influenza A is
found in a wide variety of bird and mammal species and is further divided into
subtypes based on differences in the membrane proteins hemagglutinin (HA) and
neuraminidase (NA).

H6N1 is a subtype of Influenza A. Hemagglutinin (HA) is a single-pass type
I integral membrane glycoprotein from the influenza virus, and comprises
over 80% of the envelope proteins present in the virus particle. The HA is a
trimer with a receptor binding pocket on the globular head of each monomer. In
natural infection, inactive HA is matured into HA1 and HA2 outside the cell by
one or more trypsin-like, arginine-specific endoprotease secreted by the
bronchial epithelial cells. Binding of HA to sialic acid-containing receptors
on the surface of its target cell brings about the attachment of the virus
particle to the cell and forms a endosome. Low pH in endosomes induce an
irreversible conformational change in HA2, releasing the hydrophobic portion
“fusion peptide”. After which, virus penetrates the cell and pours its contents
including the RNA genome into the cytoplasm mediated by fusion of the
endocytosed virus particle’s own membrane and the endosomal membrane.
Hemagglutinin plays a major role in the determination of host range restriction
and virulence.