太鼎生物科技/太鼎食安科技

GenScript 內毒素消除試劑

內毒素 (Endotoxin) 簡介

內毒素來源為革蘭式陰性菌細胞壁。成分為脂多醣體 (Lipopolysaccharide, LPS)。其結構組成：1. 脂質A (lipid A) 2. 多醣類核心 (core polysaccharides) 3. O-多醣類 (O-polysaccharide)

引發症狀：血管內凝集血栓症、敗血性休克

Endotoxin (LPS) is released
primarily upon cell lysis when bacterial cell dies can make up the majority of
pyrogens. Endotoxin removal is especially important when performing
immunological readouts and developing manufacturing processes because endotoxin
can cause false readings in cell based assays and there are limits to the
amount of endotoxin allowed in human products. It is always desirable to
rapidly and effectively remove pyrogen from pharmaceutical products,
recombinant proteins produced in E. coli (or other gram negative
bacteria), and tissue culture media.

ToxinEraser Endotoxin Removal Kit

產品特點：

1. 高移除效率與高穩定性，可降低內毒素含量至<0.1 EU/ml

2. 高結合能力：>2 x 10⁶ EU/ml

3. 分離管柱流速快，不需抽氣幫浦

4. Resin可重複使用達五次

5. 高於90%的產品回收率

移除原理：

利用結合有modified Polymixin B的Resin, 與endotoxin中的Lipid A作結合

應用領域：

重組蛋白生產, 動物實驗用試劑, 藥物合成, 醫療用溶液製作(ex. 生理食鹽水, 腎臟透析液)

Ordering
Information

Related
Products