ELISA Kit for Retinol Binding Protein 4, Plasma
(RBP4)
Retinol
Binding Protein 4, Plasma (RBP4)
PDF RBP4 ELISA套組操作手冊下載, 貨號#E90929Hu
測量範圍 | 9.38-600ng/mL |
靈敏度 | 3.35ng/mL |
Retinol binding protein (RBP) 4 is the only specific
transport protein for vitamin A in the circulation whose function is to deliver
vitamin to target tissues. In obesity and type 2 diabetes, expression of Glut4
is significantly impaired in adipocytes. Glucose transport via Glut4 is the
rate-limiting step for glucose use by muscle and adipose tissue.
Yang et al. noted that
adipocytespecific deletion of Gluts led to notable elevation of RBP4 causing
systemic insulin resistance, and that reduction of RBP4 improved insulin
resistance. This identified a novel role of RBP4 in regulating insulin action
and RBP4 is recorded as an adipocytederived hormone. Thus, measurement of serum
or plasma RBP4 is a useful means for understanding of metabolic disorders.
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