NFkB活化與發炎、癌症生成有密切關係，因此，目前多數研究皆致力於研發NFkB活化之抑制劑，以期具有抗發炎及治療癌症之療效。Abmgood及BIOVISION提供多項研究NFkB之抗體、ELISA KIT、抑制劑。產品種類齊全，是您最佳的選擇
【NFkb產品介紹】 NFkB was
identified as a sequence specific transcriptional activator that binds to the
intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a
heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa
transactivation subunit (p65/RelA). Both of these subunits exhibit sequence
homology to the protooncogene c-Rel. The p50/p65 heterodimer remains in the
cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation
of cells by a wide variety of stimuli such as lipopolysaccharide (LPS),
pro-inflammatory cytokines, and viral infection. IkB is phosphorylated and
degraded by proteosome. The active NFkB heterodimer is translocated into the
nucleus and induces gene expression.
Product | Size | Concentration | Cat. No. |
|
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100ug | 1ug/ul | Y011010 | $7500 | ||
100ug | 1ug/ul | Y011011 | $7500 | ||
100ug | 1ug/ul | Y011012 | $7500 | ||
100ug | 1ug/ul | Y011013 | $7500 | ||
100ug | 1ug/ul | Y011014 | $7500 | ||
NF-kB p100/p52 (Phospho-Ser865) | 100ug | 1ug/ul | Y011015 | $7500 | |
NF-kB p100/p52 (Phospho-Ser869) | 100ug | 1ug/ul | Y011016 | $7500 | |
NF-kB p105/p50 (Phospho-Ser337) | 100ug | 1ug/ul | Y011017 | $7500 | |
NF-kB p105/p50 (Phospho-Ser893) | 100ug | 1ug/ul | Y011018 | $7500 | |
NF-kB p105/p50 (Phospho-Ser907) | 100ug | 1ug/ul | Y011019 | $7500 | |
100ug | 100ug/100ul | Y011166 | $7500 | ||
100ug | 1ug/ul | Y011217 | $7500 | ||
100ug | 1ug/ul | Y011260 | $7500 | ||
NFκB-p105/p50 (Phospho-Ser927) | 100ug | 100ug/100ul | Y011312 | $7500 | |
100ug | 1ug/ul | Y021010 | $6000 | ||
100ug | 1ug/ul | Y021011 | $6000 | ||
100ug | 1ug/ul | Y021012 | $6000 | ||
100ug | 1ug/ul | Y021013 |
|
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