太鼎生物科技/太鼎食安科技

  

【產品名稱】 Influenza A H1N1 (
A/California/04/2009 ) Neuraminidase 蛋白質

【產品規格】200ug、500ug、1mg

【產品Datasheet】11058-V07H (200ug)

Synonym:	NA
Protein Construction:	A DNA sequence encoding the mature form of Influenza A virus ( A/California/04/2009 (H1N1) ) Neuraminidase ( ACP41107.1 )( His 36 - Lys 469 )was fused with a polyhistidine tag at the N-terminus
Source:	Influenza A H1N1
Expression Host:	Human Cells

【產品特點】

H1N1 NA Protein QC Testing

Purity:	> 73 % as determined by SDS-PAGE	SDS-PAGE:   H1N1 NA protein
Bio-activity:	Inactive
	For active Neuraminidase (NA), please see H1N1 NA.
Endotoxin:	< 1.0 EU per μg of the protein as determined by the LAL method.
Stability:	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal:	His
Molecular Mass:	The recombinant influenza H1N1 virus neuraminidase ( A/California/04/2009 (H1N1) ) comprises 450 amino acids with the predicted molecular mass of 50 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 65-75 kDa in SDS-PAGE under reducing conditions
Formulation:	Lyophilized from sterile PBS, pH 7.4

【產品保存方法】

H1N1 NA Protein Usage
Guide

Storage:	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

【其它相關產品】

H1N1 NA Protein Related
Products & Topics

Related Areas:

Enzyme>>Carbohydrate Metabolism Enzymes>>H1N1 neuraminidase/H1N1 NA

Immunology>>Innate Immunity>>Lysosomal Enzyme>>H1N1 neuraminidase/H1N1 NA

Virus>>Influenza Virus>>H1N1 neuraminidase/H1N1 NA

【其它NA蛋白質產品】

Products	Source (CLICK for detailed Info. and Price)	Molecule	Description	Cat. No
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	Fc Tag	11058-V01H
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	His Tag	11058-V07H
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	His Tag	11058-V07B
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	His Tag	11058-V07HC
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	-	11058-VNAHC
Protein	Influenza Neuraminidase (NA) H1N1, A/California/04/2009	NA	-	11058-VNAHC1

【H1N1流感NA抗體】

Antibodies:

Products	Antigen Source (CLICK for detailed Info. and Price)	Antigen Molecule	Application	Cat No
MAb	Influenza Antibody to H1N1, Mouse Anti H1N1 MAb	NA	WB, ELISA	11058-MM04

【相關流感研究試劑】

Related Influenza Virus
Research Tools

·       Influenza Virus Research Tools

·       Influenza Neuraminidase & Antibody

·       Influenza Neuraminidase (NA)

·       H1N1 Neuraminidase

·       A/California/04/2009

【H1N1蛋白質介紹】H1N1 NA Protein
Description

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins
found on the surface of influenza virus. NA, also called sialidases,
specifically catalyze the hydrolysis removal of terminal sialic acid residues
from viral and cellular glycoconjugates. It is known that HA binds to the
sialic acid-containing receptors on the surface of host cells during initial
infection, and at the end of an infectious cycle, NA cleaves the HA-sialic acid
bondage from the newly formed virions and the host cell receptors during
budding. NA is described as a receptor-destroying enzyme which facilitates
virus release and efficient spread of the progeny virus from cell to cell. NA
is a single-pass type I I membrane protein which exists as a homotetramer, and
the transmembrane domain is involved in lipid raft association during
intracellular transport. NA is suggested to play a role in the determination of
host range restriction on replication and virulence. Nine subtypes of NA have
been identified, and subtypes N1 and N2 have been positively linked to
epidemics in man.

【文獻參考】References

1.    Barman, S. et al., 2000, J. Virol. 74: 6538-6545.

2.    Colman, PM. et al., 1983, Nature. 303: 41-44.

3.    Suzuki, T. et al., 2005, J. Virol. 79: 11705-11715.

4.    von, Itzstein, M. 2007, Nat. Rev. Drug. Discov. 6:
967-974.

【產品訂購資訊】

【供應廠商】太鼎生物科技有限公司

【連絡人】許虹宜0920-312382

【台北公司】02-86609496
【台中公司】0935229803

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