太鼎生物科技/太鼎食安科技

Rapamycin 免疫抑制劑, 5g

Rapamycin

Catalog#: 1568-5  | Size: 5
mg

Rapamycin作用

Rapamycin，雷帕黴素，是新型大環內酯的抗排斥藥物，是目前世界上最新的強效免疫抑制劑，臨床上用於器官移植的抗排斥反應和自身免疫性疾病的治療。可能通過阻斷IL-2啟動的T細胞增殖而選擇性抑制T細胞，用於抗移植排斥反應。2009年7月的《Nature》雜誌上，文章Rapamycin fed from 20 months of
age extends lifespan in genetically heterogeneous mice，研究顯示此類藥物能延長酵母菌、線蟲、果蠅等無脊椎動物的壽命。(資料來源http://www.ebiotrade.com/newsf/2010-2/2010223171552934.htm)

產品資料

Alternate
Name/Synonyms: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine,
AY 22989, Sirolimus

Appearance: Off-white solid

Formulation: N/A

CAS Number: 53123-88-9

Molecular
Formula: C₅₁H₇₉NO₁₃

Molecular
Weight: 914.19

Purity: ≥99%

Solubility: DMSO and EtOH

Storage Temp.: -20°C

Shipping
Conditions: gel
pack

Description: An immunosuppressant.
Selectively blocks signaling that leads to p70 S6 kinase activation (IC50 = 50
pM). Inhibits lymphokine-induced cell proliferation at the G1 phase. Induce apoptosis
in a murine B cell line. Rapamycin has been used in vivo studies by i.p., i.m.,
and i.v. administrations..

Handling: Protect from light and
moisture

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