HSPG2 antibody
Catalog No. | A92748Hu01 | Organism | Homo sapiens (Human) |
Applications | WB, ICC, IHC-P, IHC-F, ELISA | ||
Certification | | ||
Clonality | Polyclonal | ||
Concentration | 200ug/ml | ||
Host | Rabbit | ||
U O M | 50ug / 100ug |
Heparan Sulfate Proteoglycan 2 (HSPG2).
Perlecan is a large multidomain
proteoglycan that binds to and cross-links many extracellular matrix (ECM)
components and cell-surface molecules.Perlecan is synthesized by both vascular
endothelial and smooth muscle cells and deposited in the extracellular matrix.
Perlecan is highly conserved across species and the available data indicate
that it has evolved from ancient ancestors by gene duplication and exon
shuffling.Perlecan is a key component of the vascular extracellular matrix,
here it interacts with a variety of other matrix components and helps to
maintain the endothelial barrier function. Perlecan is a potent inhibitor of
smooth muscle cell proliferation and is thus thought to help maintain vascular
homeostasis. Perlecan can also promote growth factor activity and thus
stimulate endothelial growth and re-generation.
[供應廠商】太鼎生物科技有限公司
【連絡人】許虹宜 0920-312382
【E-mail】taiding.biotech@msa.hinet.net
【臺北公司】02-86609496
【相關網址】www.biopioneer.com.tw
【原廠網址】www.uscnlife.com
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