【TREVIGEN產品】Genomic Instability and Genotoxic Stress DNA Repair Gene Knockdown Cell Lines－太鼎生物科技/太鼎食安科技

Trevigen is pleased to provide highly qualified enzymes, antibodies, and assay kits for DNA damage and repair research. As always, our products are accompanied by detailed product data sheets or instructions for use, and backed with expert technical support.

DNA Repair Deficient Cell Lines

DNA repair pathways maintain the integrity of the genome reducing the onset of cancer, disease and aging phenotypes. To further study repair pathways, Trevigen offers panels of human cell lines each deficient in proteins associated with DNA repair. The first panel consists of cell lines deficient for proteins in the Base Excision Repair Pathway. For the availability of other DNA repair deficient cell lines contact Trevigen.

Catalog #	Product Name	# of Cells Per Vial	Size	%KD by RT-PCR
5500-001-01	PARP1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	72%
5501-001-01	PARG Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	84%
5502-001-01	BRCA1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	83%
5503-001-01	Knock Down Control Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	N/A
5504-001-01	OGG1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	63%
5505-001-01	NTHL1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	91%
5507-001-01	NEIL2 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	86%
5508-001-01	NEIL3 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	95%
5509-001-01	UNG Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	87%
5510-001-01	SMUG1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	63%
5511-001-01	MPG Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	98%
5512-001-01	MultYH Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	87%
5513-001-01	Neil1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	92%
5514-001-01	PARP2 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	83%
5515-001-01	PARP3 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	70%
5516-001-01	XRCC1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	81%
5517-001-01	APE1 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	90%
5518-001-01	APE2 Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	80%
5519-001-01	TDG Knock Down Cell Line (MTA Required prior to shipment)	1x10⁶	1 vial	74%

PARP/PAR/PARG

PARP-1 contributes to the sequence of events that occurs during DNA base excision repair. Trevigen offers kits that measure the in vivo and in vitro activities of PARP and PARG.

CometAssay®

The single cell gel electrophoresis or CometAssay® is a state-of-the-art technique for quantitating DNA damage and repair from in vivo and in vitro samples of eukaryotic cells and some prokaryotic cells. In conjunction with Trevigen’s new CometAssay® Electrophoresis System, which eliminates known causes of assay variability, it is the only technique that directly measures DNA damage in individual cells and as a result has rapidly gained importance in the fields of genetic toxicology and human biomonitoring.

DNA Repair Enzymes and Antibodies

Trevigen’s unique FLARE™ Assays characterize DNA damage in single cells using a variety of DNA repair enzymes that recognize oxidative and UV damage in conjunction with Trevigen’s CometAssay® Electrophoresis System. A variety of DNA repair enzymes and antibodies are available as individual components with optimized assay conditions and buffers for research in areas of double-strand break repair, base excision repair, DNA methylation, oxidative damage, UV damage, and radiation damage.