DUB相關抑制劑/ P22077 貨號#2301-5
P22077 是ubiquitin-specific
protease USP7(泛素特異性蛋白酶USP7)抑制劑,EC50為8.6 μM, 也抑制緊密相關的去泛素化酶(DUB) USP47。
A USP7/USP47 inhibitor
Product Name: USP7/USP47
Inhibitor, P 22077
Alternate Name/Synonyms: 1-(5-(2,4-Difluorophenylthio)-4-nitrothiophen-2-yl)ethanone;
DUB inhibitor
Description: A cell-permeable inhibitor of the
ubiquitin-specific protease (IC₅₀ = 8.6 µM) and
the closely related deubiquitinase (DUB) USP47. P22077 displays weak or no
inhibition (EC₅₀>50 µM) towards a panel of 14
isopeptidases and other proteases. Inhibits USP7-mediated p53 deubiquitination.
Peptide Sequence: No
Appearance: Yellow solid
Formulation: N/A
CAS Number: 1247819-59-5
Molecular Formula: C12H7F2NO3S
Molecular Weight: 315.32
Purity: ≥98% by HPLC
Solubility: DMSO (~ 30 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
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DUB相關抑制劑
RELATED PRODUCTS:
LDN-57444 (Cat. No. 2016-5, 25)
Spautin-1 (Cat. No. 2037-5, 25)
USP14 Inhibitor, IU-1 (Cat. No. 1845-5, 25)
USP7/USP47 Inhibitor P22077 (Cat. No. 2301-5, 25)
WP-1130 (Cat. No. 2014-5, 25)
【連絡人】許虹宜 0920-312382 Hung-Yi Hsu
【E-mail】taiding.biotech@msa.hinet.net
【公司電話】02-86609496【公司傳真】02-86609342
【相關網址】www.biovision.com
【公司網址】www.biopioneer.com.tw
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